- Trials with a EudraCT protocol (5)
- Paediatric studies in scope of Art45 of the Paediatric Regulation (0)
5 result(s) found for: Trk Receptor.
Displaying page 1 of 1.
EudraCT Number: 2017-004246-20 | Sponsor Protocol Number: 20810 | Start Date*: 2018-03-06 | ||||||||||||||||
Sponsor Name:Bayer Consumer Care AG | ||||||||||||||||||
Full Title: A Phase 1 Study of the TRK Inhibitor Selitrectinib (BAY 2731954) in Adult and Pediatric Subjects with Previously Treated NTRK Fusion Cancers Formerly: A Phase 1/2 Study of the TRK Inhibitor LOXO-1... | ||||||||||||||||||
Medical condition: NTRK fusion cancers previously treated with a TRK inhibitor | ||||||||||||||||||
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Population Age: Infants and toddlers, Children, Adolescents, Under 18, Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: DK (Completed) FR (Ongoing) DE (Completed) ES (Completed) GB (GB - no longer in EU/EEA) IE (Completed) IT (Ongoing) BE (Completed) | ||||||||||||||||||
Trial results: View results |
EudraCT Number: 2014-001342-21 | Sponsor Protocol Number: NCTUTRK1(6840) | Start Date*: 2014-09-04 |
Sponsor Name:Newcastle upon Tyne Hospitals NHS Foundation Trust | ||
Full Title: Topical tropomysin kinase (TRK) inhibitor as a treatment for inherited CYLD defective skin tumours (TRAC) | ||
Medical condition: Patients with germline CYLD mutations (OMIM 605018). These include Brooke-Spiegler Syndrome, familial cylindromatosis and multiple familial trichoepitheliomas (OMIM #605041, #132700, #601606 respec... | ||
Disease: | ||
Population Age: Adults, Elderly | Gender: Male, Female | |
Trial protocol: GB (Completed) | ||
Trial results: View results |
EudraCT Number: 2015-003582-28 | Sponsor Protocol Number: LOXO-TRK-15002 | Start Date*: Information not available in EudraCT | |||||||||||
Sponsor Name:Bayer Consumer Care AG | |||||||||||||
Full Title: A Phase 2 Basket Study of the Oral TRK Inhibitor larotrectinib in Subjects with NTRK Fusion-Positive Tumors | |||||||||||||
Medical condition: Solid Tumors | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (GB - no longer in EU/EEA) DK (Trial now transitioned) IE (Restarted) ES (Ongoing) PT (Trial now transitioned) FR (Ongoing) DE (Ongoing) SE (Ongoing) BE (Ongoing) CZ (Completed) SK (Completed) NO (Completed) HU (Completed) PL (Completed) GR (Completed) IT (Prematurely Ended) | |||||||||||||
Trial results: (No results available) |
EudraCT Number: 2016-004987-21 | Sponsor Protocol Number: ONO-7579-01 | Start Date*: 2017-09-13 | |||||||||||
Sponsor Name:Ono Pharmaceutical Co., Ltd. | |||||||||||||
Full Title: An open-label, multi-center, dose-escalation and expansion study to evaluate the safety and efficacy of ONO-7579 in patients with advanced solid tumors/ NTRK gene fusion positive advanced solid tumors | |||||||||||||
Medical condition: Advanced solid tumors and Neurotrophic receptor tyrosine kinase (NTRK) gene fusion positive advanced solid tumors | |||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | ||||||||||||
Trial protocol: GB (Prematurely Ended) | |||||||||||||
Trial results: View results |
EudraCT Number: 2015-003385-84 | Sponsor Protocol Number: GO40782(RXDX-101-02) | Start Date*: 2016-03-15 | ||||||||||||||||
Sponsor Name:F. Hoffman-La Roche Ltf | ||||||||||||||||||
Full Title: AN OPEN-LABEL, MULTICENTER, GLOBAL PHASE 2 BASKET STUDY OF ENTRECTINIB FOR THE TREATMENT OF PATIENTS WITH LOCALLY ADVANCED OR METASTATIC SOLID TUMORS THAT HARBOR NTRK1/2/3, ROS1, OR ALK GENE REARRA... | ||||||||||||||||||
Medical condition: Locally Advanced or Metastatic Solid Tumors that Harbor NTRK1/2/3, ROS1, or ALK Gene Rearrangements | ||||||||||||||||||
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Population Age: Adults, Elderly | Gender: Male, Female | |||||||||||||||||
Trial protocol: BE (Completed) DE (Ongoing) ES (Ongoing) NL (Ongoing) PL (Ongoing) IT (Ongoing) | ||||||||||||||||||
Trial results: (No results available) |
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